Jason® membrane

NATIVE PERICARDIUM MEMBRANE FOR GBR/GTR

 

JJason® membrane is a native collagen membrane obtained from porcine pericardium, developed and manufactured for dental tissue regeneration. It is very thin and provides a naturally long barrier function based on the specific composition and structure of the pericardial collagen fibres. Owing to the preservation of the natural biomechanical properties of the pericardium, Jason® membrane exhibits beneficial handling characteristics such as a remarkable tear resistance and effective surface adaptation.

 

JASON® MEMBRANE IS A VERY THIN COLLAGEN MEMBRANE OFFERING A NATURALLY LONG BARRIER FUNCTION AND FAVORABLE HANDLING CHARACTERISTICS

Due to the unique production process, the superior properties of the native pericardium are preserved during the extensive cleaning procedure that is applied for the production of Jason® membrane. Therefore, Jason® membrane shows a natural comb-like, multilayered collagen structure with an increased content of collagen type III leading to a remarkable tear resistance and slow degradation of Jason® membrane. This ensures a natural long barrier function, making the Jason® membrane our recommended choice particularly for large augmentative procedures.

CLINICAL APPLICATION

Single tooth restauration with maxgraft® cortico and Jason® membrane

Dr. K. Chmielewski
Gdansk, Poland

Treatment of dehiscence defect with cerabone® and Jason® membrane

Dr. S. Stavar
Houten, Netherlands

PROPERTIES

  • Naturally long barrier function
  • Multi-directional strength and tear resistance
  • No stickiness after rehydration
  • Excellent surface adaptation and reduced risk of swelling
  • Easy manipulation, can be applied dry or wet
  • Low thickness
  • Fast vascularization due to three-dimensional structure

UPCOMING EVENTS

Hong Kong, 31.8.-3.9.2017

Dr. Marius Steigmann: Soft Tissue Mangement in Implant Dentistry – Module 3

Manila, 12-13 Sept. 2017

More Events on botiss-academy

INDICATIONS

Jason® membrane offers a naturally long barrier function, which is especially advantageous for the regeneration of larger defects or more extended augmentative procedures. Due to its low thickness, Jason® membrane is particularly beneficial in patients with thin biotypes or, generally, if a tension free closure of the flap is difficult.

 

Implantology, Periodontology and Oral and CMF Surgery

  • Horizontal and vertical augmentation
  • Ridge reconstruction
  • Socket and ridge preservation
  • Sinus lift
  • Fenestration and dehiscencedefects
  • Intraosseous defects (1 to 3 walls)
  • Furcation defects (class I and II)

Further handling tips, clinical cases and videos on Jason® membrane can be found in the

INDICATION MATRIX.

 

DETAILS

SPECIFIC FACTS

NATIVE 3D COLLAGEN STRUCTURE
Natural three-dimensional collagen network of Jason® membrane

Natural three-dimensional collagen
network of Jason® membrane

Jason® membrane is a native collagen membrane derived from porcine pericardium (strong, elastic membrane that circumvents and protects the heart). During the extensive wet chemical cleaning procedure of the manufacturing process, all antigenic components are removed, but the natural structure of aligned collagen fibers and interconnected pores [1,2] is preserved leading to slow degradation and prolonged stability.

Beneficial handling characteristics

IMG_0209According to the biomechanical properties of native pericardium, which is able to withstand significant volume changes and forces, the Jason® membrane exhibits a remarkable tear resistance and stability. Accordingly, Jason® membrane is characterized by an outstanding multi-directional tear resistance that allows easy pinning and suturing without rupturing and very good surface adaption without stickiness upon rehydration.

Low thickness

Bild3The thickness of a membrane does not necessarily correspond to its barrier function and resorption time. Jason® membrane offers a very low thickness of ~0.1-0.2 mm, but nevertheless exhibits a prolonged resorption time as proven by animal experiments [3].

Naturally long barrier function

The Jason® membrane is a native collagen membrane, meaning the natural collagen structure of the pericardium is preserved during the manufacturing process. Due to the comb-like and multilayered collagen structure with an increased content of collagen type III, the Jason® membrane shows a slow
degradation [2,3]. This ensures a prolonged barrier function, making
the Jason® membrane our recommended choice particularly for
large augmentative procedures.

No chemical cross-linking

Jason® membrane is not artificially cross-linked by chemical or physical treatment. Cross-linking slows down membrane degradation properties and negatively affects the biocompatibility, tissue integration, and revascularization as shown for other collagen membranes by an animal study [4].

In opposite to chemically or physically cross-linked membranes, Jason® membrane is characterized by a naturally long barrier function based on its origin from pericardial tissue [3]. The fibres of the original pericardial tissue are naturally cross-linked, their structure being preserved during the entire production process, thus generating a natural collagen membrane with an extended degradation time [1,2,3].

No fixation necessary

Bild4The Jason® membrane is hydrophilic and rapidly rehydrates in blood. The excellent ability of the Jason® membrane to adhere to the defect site without sticking together when folded guarantees optimal handling. The excellent adhesion to the defect site makes additional fixation of the Jason® membrane unnecessary in most cases. If wished or necessary, the multidirectional strength and tear resistance of Jason® membrane permits the use of sutures and other fixation methods (e.g. pinning).

Product Specifications

Jason® membrane is provided in the following dimensions:

Art.-No. Size Content
681520 15 × 20 mm 1 membrane
682030 20 × 30 mm 1 membrane
683040 30 × 40 mm 1 membrane

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LITERATURE

[1]  Stähli, A., Miron, R.J., Bosshardt, D.D., Sculean, A. and Gruber, R. (2016), Journal of Periodontology, Vol. 87 No. 5, pp. 583–590.
[2]  Rothamel, D., Schwarz, F., Fienitz, T., Smeets, R., Dreiseidler, T., Ritter, L., Happe, A. and Zöller, J. (2012), The International journal of oral & maxillofacial implants, Vol. 27 No. 1, pp. 146–154.
[3]  Rothamel, D., Fienietz, T., Benner, M., Happe, A., Kreppel, M., Scheer, M., Zöller, J. (2011), Poster EAO, Biodegradation pattern of native and cross-linked porcine collagen matrices – an experimental study in rats
[4]  Rothamel, D., Schwarz, F., Sager, M., Herten, M., Sculean, A. and Becker, J. (2005), Clinical oral implantsresearch, Vol. 16 No. 3, pp. 369–378.